Actually not. Enclosure as it is, it's designed to fit MK2/MK3 printer, but it can be enlarged in any direction to accomodate larger or smaller printer. That means if prusa is for example 500mm wide and you printer is 600mm wide, you can add 100mm to those extrusions that goes from left to right and also add 100mm to the front and back panels. It's very simple to make the new dimensions and the build is basically the same, just the elements are larger/smaller.
Have a nice day and greetings from Slovenia!=)