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Yes, as the power/current draw is too high for the Y and Z axis drivers on the RUMBA board, the x-axis NEMA23 and extruder motors will work fine of the board

There is an image of the wiring (Sub33d_v3.07_stepper_and_heatbed_wiring_diagram_v1.00.zip), which can be used to connect many different 3D printer boards to external CNC type drivers, I used the RAMPS 1.4 in the wiring diagram as this seems to be one of the most common boards.