I find the ABS fumes really smelly and I do have a little fear for potential health risks (Even in a well ventilated room I get headaches when I stand near the printer).
So to be better save than sorry I made this simple yet effective fume cabinet. When you have all the materials you can build this in 1 a 2 hours.
-A plastic storage container. Just look for one that has the right dimensions, for the Up! plus you need a box that is about L 45 cm x W 44 cm x h 45 cm.
-A PC fan. I used a 120 mm fan.
-A 12 volt ac adapter.
-A female connector to connect the PC fan to adapter (solder the positive en negative wire of the fan to the connector).
-120mm Fan to 100mm A/C Duct Adaptor ( http://www.thingiverse.com/thing:37770 ). This model fits exactly in the 120 x 120 footprint of the up! plus but make sure you place the clamps right on the edge of the platform!